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Our Research

Current Projects

Examples of our current projects are provided in the sections below to help you understand more about our work.

The examples relate our different stakeholder types, including industry, clinical partners, NIHR Infrastructures, regulatory (and other) agencies, and academia.

Projects with Industry

Primary care

  • Point-of-care test (POCT) for C-reactive protein. Exploring the potential of a new device in pharmacies.
  • Novel hearing test. We are analysing stakeholder needs and preferences, and identifying barriers to adoption.

Infectious diseases

  • POCT for acute HIV infections. We are conducting stakeholder and economic analysis.
  • New rapid POCT to identify species-specific bacterial infection. We are conducting a clinical study and assessing stakeholder perceptions. We are also performing economic analysis.

Projects with Clinical Partners

Cancer (gastrointestinal)

  • Breath test for diagnosing gastrointestinal cancers. This research addresses an unmet need for a non-invasive test to triage patients for invasive investigations. We are working closely with colleagues in the department of surgery and cancer at Imperial College to support several studies that aim to validate the breath tests and to maximize safety and usability.

Projects with other NIHR infrastructures

Imperial and Oxford AHSNs are funding three posts at London IVD to streamline the diagnostics development pathway from AHSNs. These posts help us to expand our clinical networks and provide access to NHS commissioners.

NIHR-North West London CLAHRC are informing grant applications such as SBRI phase II with Highland Biosciences Ltd. The aim is to have a diagnostic device for major trauma patients implemented in the NHS within the next five years.

Projects with agencies

The Medicines & Healthcare products Regulatory Agency (MHRA) are funding a post at London IVD to research common faults experienced by end users with diagnostic (and other) devices. This collaboration will generate a set of principles to support designers, and identify deficiencies in the current system of adverse event reporting.

The National Institute for Health and Care Excellence (NICE) are working with us to develop methods to enable the efficient and effective evaluation of diagnostic tests. We are developing an action based on a joint workshop which we facilitated in January 2017. Representatives from other agencies (MHRA, HRA, PHE) also participated in this.

Projects with other academic institutions

University College London are working with us to aid more precise drug dosing in children with cancer. Please click here for more details on this project “ChromaDose”.

Brunel University are working with us to build an innovative platform to allow flexible economic analysis of diagnostics.

King’s College London are supporting research on interruptions and multitasking in the context of diagnostics and other medical devices.


Projects you can get involved with

Study Recruitment Request

Study Title: Development of a patient centred usability evaluation tool for home medical devices

Principal Investigator: Dr Arkeliana Tase

Project Supervisors: Prof Peter Buckle, Dr Melody Zhifang, and Prof George Hanna


We are looking for patients, relatives and members of the public to take part in our study to help refine the usability tool we are developing for home use medical devices and technology.

The aim of this tool will be to empower patients to have their voices heard on their experiences and help manufacturers of medical devices improve the design of their devices based on patient requirements.

If you are interested in taking part, please contact Dr Arkeliana Tase at to organise a short discussion (20-30 minutes) on the tool being developed.

All responses will be confidential and you will not be identified in the presentation of results for this study.  



A selection of recent publications involving members of the NIHR London IVD is included below.

Markar SR, Mackenzie H, Ni M, et al. The influence of procedural volume and proficiency gain on mortality from upper GI endoscopic mucosal resection. Gut 2016

Acharya A, Markar SR, Matar M, Ni M, Hanna GB. Use of Tumor Markers in Gastrointestinal Cancers: Surgeon Perceptions and Cost-Benefit Trade-Off Analysis. Annals of surgical oncology 2016

Acharya A, Markar SR, Ni M et al. Biomarkers of acute appendicitis: Systematic review and cost-benefit trade-off analysis. Surg Endosc, 2016.

Sequential simulation (SqS) of clinical pathways: a tool for public and patient engagement in point-of-care diagnostics

Buckle, P. The Ageing Workforce in the United Kingdom and the Design of the Work System. In: Contemporary Ergonomics and Human Factors 2016 Eds: Waterson, P Hubbard  E-M & Sims, R. 2016  ISBN: 978-0-9554225-9-1 p167-168 ISBN: 978-0-9554225-9-1

Buckle, P and  Borsci, S.  Human Factors to support safe and successful healthcare products. (Workshop) In: Contemporary Ergonomics and Human Factors 2016 Eds: Waterson, P Hubbard. 2016  E-M & Sims, R  ISBN: 978-0-9554225-9-1

Buckle, P and Borsci, S. How should we communicate a human factors approach to complex systems? Abstract. Proceedings of Human Factors in Complex Systems, Publ. University Nottingham. p 69.2016

Acharya A, Markar SR, Matar M, Ni M, Hanna GB. Use of Tumor Markers in Gastrointestinal Cancers: Surgeon Perceptions and Cost-Benefit Trade-Off Analysis. Annals of surgical oncology 2016.

Acharya A, Markar SR, Ni M, Hanna GB. Biomarkers of acute appendicitis: systematic review and cost-benefit trade-off analysis. Surgical endoscopy 2016.

Huddy JR, Markar SR, Ni MZ, Morino M, Targarona EM, Zaninotto G, et al. Laparoscopic repair of hiatus hernia: Does mesh type influence outcome? A meta-analysis and European survey study. Surgical endoscopy 2016.

Huddy JR, Ni M, Mavroveli S, Barlow J, Williams DA, Hanna GB. A research protocol for developing a Point-Of-Care Key Evidence Tool ‘POCKET’: a checklist for multidimensional evidence reporting on point-of-care in vitro diagnostics. BMJ open 2015;5:e007840.

Huddy JR, Ni MZ, Barlow J, Majeed A, Hanna GB. Point-of-care C reactive protein for the diagnosis of lower respiratory tract infection in NHS primary care: a qualitative study of barriers and facilitators to adoption. BMJ open 2016;6:e009959.

Huddy JR, Ni MZ, Markar SR, Hanna GB. Point-of-care testing in the diagnosis of gastrointestinal cancers: current technology and future directions. World journal of gastroenterology 2015;21:4111-20.

Ni M, Priest P, Phillips LD, Hanna GB. Risks of Using Bedside Tests to Verify Nasogastric Tube Position in Adult Patients. EMJ Gastroenterol 2014;3:49-56.

Lim RHM, Anderson JE, Buckle PW. Work Domain Analysis for understanding medication safety in care homes in England: an exploratory study, Ergonomics, Vol: 59, Pages: 15-26. 2016. ISSN: 0014-0139

Borsci S, Buckle P, Hanna GB. Why you need to include human factors in clinical and empirical studies of in vitro point of care devices? Review and future perspectives, EXPERT REVIEW OF MEDICAL DEVICES, Vol: 13, Pages: 405-416,2016. ISSN: 1743-4440