Examples of our current projects are provided in the sections below to help you understand more about our work.
The examples relate our different stakeholder types, including industry, clinical partners, NIHR Infrastructures, regulatory (and other) agencies, and academia.
Projects with Industry
Point-of-care test (POCT) for C-reactive protein. Exploring the potential of a new device in pharmacies.
Novel hearing test. We are analysing stakeholder needs and preferences, and identifying barriers to adoption.
POCT for acute HIV infections. We are conducting stakeholder and economic analysis.
New rapid POCT to identify species-specific bacterial infection. We are conducting a clinical study and assessing stakeholder perceptions. We are also performing economic analysis.
Projects with Clinical Partners
Breath test for diagnosing gastrointestinal cancers. This research addresses an unmet need for a non-invasive test to triage patients for invasive investigations. We are working closely with colleagues in the department of surgery and cancer at Imperial College to support several studies that aim to validate the breath tests and to maximize safety and usability.
Projects with other NIHR infrastructures
Imperial and Oxford AHSNs are funding three posts at London IVD to streamline the diagnostics development pathway from AHSNs. These posts help us to expand our clinical networks and provide access to NHS commissioners.
NIHR-North West London CLAHRC are informing grant applications such as SBRI phase II with Highland Biosciences Ltd. The aim is to have a diagnostic device for major trauma patients implemented in the NHS within the next five years.
Projects with agencies
The Medicines & Healthcare products Regulatory Agency (MHRA) are funding a post at London IVD to research common faults experienced by end users with diagnostic (and other) devices. This collaboration will generate a set of principles to support designers, and identify deficiencies in the current system of adverse event reporting.
The National Institute for Health and Care Excellence (NICE) are working with us to develop methods to enable the efficient and effective evaluation of diagnostic tests. We are developing an action based on a joint workshop which we facilitated in January 2017. Representatives from other agencies (MHRA, HRA, PHE) also participated in this.
Projects with other academic institutions
Brunel University are working with us to build an innovative platform to allow flexible economic analysis of diagnostics.
King’s College London are supporting research on interruptions and multitasking in the context of diagnostics and other medical devices.
Projects you can get involved with
Study Recruitment Request
Study Title: Designing a Framework for a Targeted Medical Device Performance Reporting System (PRS)
Primary Investigator: Miss Arkeliana Tase
Supervisors: Prof Peter Buckle, Dr Melody Zhifang, Prof George Hanna
We are looking for Clinicians (especially if working in operating theatre environment) and representatives from Medical Device companies to take part in this study relating to patient safety in relation to medical devices and the process of performance reporting of medical devices.
If you are a Medical Device Company Representative/ SMEs(especially if you have direct contact with clinicians and NHS trusts) please contact myself (Dr Arkeliana Tase) email@example.com organise a short interview (about 20-30 minutes) relating the process of medical device performance reporting by healthcare professionals to yourselves.You will not be asked about particular devices and your identity will be confidential.
If you are a clinician, you will be asked to take part in the second stage of this study which involves completing an online questionnaire on the issues relating reporting of MDs and your comments on the proposed PRS. The online questionnaire will take approximately 10-15 minutes to complete and is based on the findings of the first stage of this study.
The online questionnairecan be accessed through link below.
All responses will be confidential, and you will not be asked to provide your name or contact details unless you state that you wish to receive a summary of the study results in which case you are asked to provide an email address.
Should you have any questions on this study or the process involved please do not hesitate to contact myself (Dr Arkeliana Tase) at firstname.lastname@example.org.
A selection of recent publications involving members of the NIHR London IVD is included below.
Markar SR, Mackenzie H, Ni M, et al. The influence of procedural volume and proficiency gain on mortality from upper GI endoscopic mucosal resection. Gut 2016
Acharya A, Markar SR, Matar M, Ni M, Hanna GB. Use of Tumor Markers in Gastrointestinal Cancers: Surgeon Perceptions and Cost-Benefit Trade-Off Analysis. Annals of surgical oncology 2016
Acharya A, Markar SR, Ni M et al. Biomarkers of acute appendicitis: Systematic review and cost-benefit trade-off analysis. Surg Endosc, 2016.
Sequential simulation (SqS) of clinical pathways: a tool for public and patient engagement in point-of-care diagnostics
Buckle, P. The Ageing Workforce in the United Kingdom and the Design of the Work System. In: Contemporary Ergonomics and Human Factors 2016 Eds: Waterson, P Hubbard E-M & Sims, R. 2016 ISBN: 978-0-9554225-9-1 p167-168 ISBN: 978-0-9554225-9-1
Buckle, P and Borsci, S. Human Factors to support safe and successful healthcare products. (Workshop) In: Contemporary Ergonomics and Human Factors 2016 Eds: Waterson, P Hubbard. 2016 E-M & Sims, R ISBN: 978-0-9554225-9-1
Buckle, P and Borsci, S. How should we communicate a human factors approach to complex systems? Abstract. Proceedings of Human Factors in Complex Systems, Publ. University Nottingham. p 69.2016
Acharya A, Markar SR, Matar M, Ni M, Hanna GB. Use of Tumor Markers in Gastrointestinal Cancers: Surgeon Perceptions and Cost-Benefit Trade-Off Analysis. Annals of surgical oncology 2016.
Acharya A, Markar SR, Ni M, Hanna GB. Biomarkers of acute appendicitis: systematic review and cost-benefit trade-off analysis. Surgical endoscopy 2016.
Huddy JR, Markar SR, Ni MZ, Morino M, Targarona EM, Zaninotto G, et al. Laparoscopic repair of hiatus hernia: Does mesh type influence outcome? A meta-analysis and European survey study. Surgical endoscopy 2016.
Huddy JR, Ni M, Mavroveli S, Barlow J, Williams DA, Hanna GB. A research protocol for developing a Point-Of-Care Key Evidence Tool ‘POCKET’: a checklist for multidimensional evidence reporting on point-of-care in vitro diagnostics. BMJ open 2015;5:e007840.
Huddy JR, Ni MZ, Barlow J, Majeed A, Hanna GB. Point-of-care C reactive protein for the diagnosis of lower respiratory tract infection in NHS primary care: a qualitative study of barriers and facilitators to adoption. BMJ open 2016;6:e009959.
Huddy JR, Ni MZ, Markar SR, Hanna GB. Point-of-care testing in the diagnosis of gastrointestinal cancers: current technology and future directions. World journal of gastroenterology 2015;21:4111-20.
Ni M, Priest P, Phillips LD, Hanna GB. Risks of Using Bedside Tests to Verify Nasogastric Tube Position in Adult Patients. EMJ Gastroenterol 2014;3:49-56.
Lim RHM, Anderson JE, Buckle PW. Work Domain Analysis for understanding medication safety in care homes in England: an exploratory study, Ergonomics, Vol: 59, Pages: 15-26. 2016. ISSN: 0014-0139
Borsci S, Buckle P, Hanna GB. Why you need to include human factors in clinical and empirical studies of in vitro point of care devices? Review and future perspectives, EXPERT REVIEW OF MEDICAL DEVICES, Vol: 13, Pages: 405-416,2016. ISSN: 1743-4440